What Is Melatonin and How Does It Work? (ADHD & Sleep)
19 May 2025 (updated 14 November) · Kiri Babbage
✔️ Medically Reviewed: 19 May 2025 by Anuradha Kohli

19 May 2025 (updated 14 November) · Kiri Babbage
✔️ Medically Reviewed: 19 May 2025 by Anuradha Kohli

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If you're struggling with sleep and have ADHD, you're not alone. Sleep issues can significantly impact your daily life, mood and overall wellbeing.
This comprehensive guide will help you understand melatonin, how it specifically benefits ADHD-related sleep challenges, important safety considerations, guidance tailored to the UK and practical strategies to improve your sleep and increase your quality of life.
Melatonin is a hormone naturally produced by the pineal gland in your brain, primarily responsible for regulating your sleep-wake cycles, known as circadian rhythms. Typically, melatonin levels increase in the evening, peak overnight and decrease by morning. Modern lifestyles, such as excessive screen time and irregular sleep patterns, often disrupt this natural production cycle.
Darkness triggers your brain to release melatonin, signalling your body to prepare for sleep. Conversely, exposure to bright light or screen devices suppresses melatonin production, causing difficulties falling asleep and disruptions to the sleep cycle.
Sleep problems are common among individuals with ADHD due to factors like hyperactivity, anxiety, medication side effects, or inherent neurological differences. ADHD often involves an imbalance of neurotransmitters like dopamine, which can significantly affect sleep quality.
Research indicates that melatonin supplements can effectively help people with ADHD establish healthier sleep patterns, thereby improving attention, mood regulation, emotional resilience and overall daily functioning.
Melatonin dosage should always be tailored individually based on age, body weight, severity of sleep disruption and personal response:
Immediate-release melatonin is beneficial for those struggling to fall asleep quickly, while prolonged-release forms help maintain continuous sleep through the night.
Melatonin is generally well-tolerated, but potential side effects include:
To minimise side effects, start with the lowest effective dose. Regular consultations with healthcare providers ensure safe dosage adjustments and effective management of side effects.
While melatonin generally has minimal interactions, it’s important to consult healthcare providers if you use other medications or supplements, particularly:
Obtaining melatonin via the NHS typically involves referral to a specialist (paediatrician or psychiatrist). Waiting times for appointments can vary considerably, from several weeks to months.
Private healthcare providers, such as HealthHero, offer quicker access to assessments and prescriptions, usually within one to two weeks. Initial consultations typically cost between £200–£300, providing greater flexibility and reduced waiting times.
Enhance the effectiveness of melatonin by integrating these complementary strategies:
Myth: Melatonin use leads to dependency.Fact: Melatonin is non-habit-forming and users typically experience no dependency with proper medical oversight.
Myth: Melatonin negatively affects fertility or hormonal balance.Fact: Current research does not show significant hormonal disruptions when melatonin is used responsibly and monitored by professionals.
Myth: Melatonin effectiveness wears off quickly.Fact: Adjustments in dose or timing often restore effectiveness and melatonin remains beneficial long-term when combined with healthy sleep hygiene.
Optimising your sleep environment and routines alongside melatonin usage maximises effectiveness:
Organisations: ADHD Foundation UK, Sleep Council UK
Books:
Why We Sleep by Matthew Walker
Sleep Solutions for your ADHD Child by Dr Mark Bertin
Digital Resources:
Sleep tracking apps (Sleep Cycle, SleepScore)
Mindfulness apps (Headspace, Calm)
Melatonin can be highly beneficial in managing ADHD-related sleep disturbances, significantly improving daily life and cognitive function. For best results, it should be part of a broader strategy encompassing healthy sleep habits, lifestyle modifications and complementary therapies. With careful monitoring and support from healthcare providers, including specialists at clinics like us at HealthHero, melatonin can help pave the way to better sleep, reduced ADHD symptoms and overall enhanced well-being.
Is melatonin safe for long-term use?Yes, under proper medical supervision, melatonin can safely be used long-term with periodic check-ins.
Can melatonin help with anxiety-related sleep issues?Yes, melatonin can aid relaxation and reduce sleep-related anxiety, particularly when combined with mindfulness or relaxation techniques.
What if melatonin stops working effectively?Consult your healthcare provider to reassess your dosage, timing, or to explore complementary approaches.
Can melatonin help shift-workers or frequent travellers with ADHD?Absolutely. Melatonin effectively adjusts sleep cycles disrupted by irregular hours or travel across time zones.

I am a late diagnosed ADHD woman with 15 years+ in copywriting, storytelling and brand narrative. I take complex health language and shape it into clean, human guidance. I write for HealthHero because people deserve information that helps them feel understood and in control of their health.