What Is Melatonin and How Does It Work? (ADHD & Sleep)
19 May 2025 · HealthHero
✔️ Medically Reviewed: 19 May 2025 by Dr.Kohli

If you're struggling with sleep and have ADHD, you're not alone. Sleep issues can significantly impact your daily life, mood and overall wellbeing.
This comprehensive guide will help you understand melatonin, how it specifically benefits ADHD-related sleep challenges, important safety considerations, guidance tailored to the UK and practical strategies to improve your sleep and increase your quality of life.
Firstly, what is Melatonin?
Melatonin is a hormone naturally produced by the pineal gland in your brain, primarily responsible for regulating your sleep-wake cycles, known as circadian rhythms. Typically, melatonin levels increase in the evening, peak overnight and decrease by morning. Modern lifestyles, such as excessive screen time and irregular sleep patterns, often disrupt this natural production cycle.
How Melatonin works
Darkness triggers your brain to release melatonin, signalling your body to prepare for sleep. Conversely, exposure to bright light or screen devices suppresses melatonin production, causing difficulties falling asleep and disruptions to the sleep cycle.
Melatonin’s role in ADHD
Sleep problems are common among individuals with ADHD due to factors like hyperactivity, anxiety, medication side effects, or inherent neurological differences. ADHD often involves an imbalance of neurotransmitters like dopamine, which can significantly affect sleep quality.
Research indicates that melatonin supplements can effectively help people with ADHD establish healthier sleep patterns, thereby improving attention, mood regulation, emotional resilience and overall daily functioning.
Melatonin dosages and recommendations
Melatonin dosage should always be tailored individually based on age, body weight, severity of sleep disruption and personal response:
- Children (6–12 years): Begin with 0.5mg–1mg approximately 30–60 minutes before bedtime.
- Adolescents (13–17 years): Typically recommended doses range from 1–3mg.
- Adults: Usually 2–5mg, often starting with prolonged-release formulations to maintain sleep throughout the night.
Immediate-release melatonin is beneficial for those struggling to fall asleep quickly, while prolonged-release forms help maintain continuous sleep through the night.
Potential side effects and safety concerns
Melatonin is generally well-tolerated, but potential side effects include:
- Daytime drowsiness or fatigue
- Mild headaches
- Dizziness or nausea
- Vivid or unusual dreams
To minimise side effects, start with the lowest effective dose. Regular consultations with healthcare providers ensure safe dosage adjustments and effective management of side effects.
Melatonin interactions with medications & supplements
While melatonin generally has minimal interactions, it’s important to consult healthcare providers if you use other medications or supplements, particularly:
- ADHD medications (usually safe, but professional guidance recommended)
- Antidepressants or mood stabilisers
- Sedatives or benzodiazepines
- Blood pressure medications
- Additional sleep aids or herbal supplements
Melatonin prescription & availability in the UK
NHS prescription
Obtaining melatonin via the NHS typically involves referral to a specialist (paediatrician or psychiatrist). Waiting times for appointments can vary considerably, from several weeks to months.
Private prescription
Private healthcare providers, such as HealthHero, offer quicker access to assessments and prescriptions, usually within one to two weeks. Initial consultations typically cost between £200–£300, providing greater flexibility and reduced waiting times.
Alternative and complementary approaches
Enhance the effectiveness of melatonin by integrating these complementary strategies:
- Magnesium supplements: Helps calm the nervous system and supports deeper, more restful sleep.
- Mindfulness and relaxation techniques: Regular practice can significantly reduce anxiety and help quiet a restless mind at bedtime.
- Structured bedtime routines: Gentle stretching, reading, or warm baths help signal your body that it's time to unwind.
Myths and misconceptions about Melatonin
Myth: Melatonin use leads to dependency.Fact: Melatonin is non-habit-forming and users typically experience no dependency with proper medical oversight.
Myth: Melatonin negatively affects fertility or hormonal balance.Fact: Current research does not show significant hormonal disruptions when melatonin is used responsibly and monitored by professionals.
Myth: Melatonin effectiveness wears off quickly.Fact: Adjustments in dose or timing often restore effectiveness and melatonin remains beneficial long-term when combined with healthy sleep hygiene.
Practical sleep guide
Optimising your sleep environment and routines alongside melatonin usage maximises effectiveness:
- Consistency: Regular sleep and wake times are crucial.
- Environment: Keep your room cool, quiet and dark.
- Pre-sleep routine: Engage in relaxing activities before bed.
- Limiting screen time: Avoid exposure to screens at least an hour before bedtime.
- Dietary adjustments: Limit caffeine and sugary snacks in the evening; opt instead for protein-rich snacks.
- Weighted blankets: These can reduce anxiety and improve sleep quality significantly.
Special considerations
- Travel with Melatonin: Keep prescriptions clearly labelled and carry a letter from your doctor, especially when travelling internationally.
- Adjusting dosages: Discuss any required dosage adjustments during periods of heightened stress, exams, or significant life changes with your healthcare provider.
Additional recommendations & resources
Organisations: ADHD Foundation UK, Sleep Council UK
Books:
Why We Sleep by Matthew Walker
Sleep Solutions for your ADHD Child by Dr Mark Bertin
Digital Resources:
Sleep tracking apps (Sleep Cycle, SleepScore)
Mindfulness apps (Headspace, Calm)
Melatonin can be highly beneficial in managing ADHD-related sleep disturbances, significantly improving daily life and cognitive function. For best results, it should be part of a broader strategy encompassing healthy sleep habits, lifestyle modifications and complementary therapies. With careful monitoring and support from healthcare providers, including specialists at clinics like us at HealthHero, melatonin can help pave the way to better sleep, reduced ADHD symptoms and overall enhanced well-being.
FAQs
Is melatonin safe for long-term use?Yes, under proper medical supervision, melatonin can safely be used long-term with periodic check-ins.
Can melatonin help with anxiety-related sleep issues?Yes, melatonin can aid relaxation and reduce sleep-related anxiety, particularly when combined with mindfulness or relaxation techniques.
What if melatonin stops working effectively?Consult your healthcare provider to reassess your dosage, timing, or to explore complementary approaches.
Can melatonin help shift-workers or frequent travellers with ADHD?Absolutely. Melatonin effectively adjusts sleep cycles disrupted by irregular hours or travel across time zones.